IndraLab

Source-Target Gene Analysis

This application analyzes relationships between a source gene and its downstream target genes using INDRA CoGEx. The analysis reveals various types of biological relationships and shared mechanisms.
The corresponding REST API endpoint for the source-target queries is /api/explain_downstream. You can find it on the API Docs under the section 'Analysis Queries'.
This tool helps understand how genes interact and influence each other in biological networks.

The analysis includes:
  • INDRA statements showing direct relationships and evidence
  • Shared biological pathways from REACTOME and WikiPathways
  • Protein family relationships
  • Gene Ontology (GO) term analysis
  • Upstream regulatory mechanisms

Enter the source gene symbol (e.g., BRCA1)
Enter target gene symbols, separated by commas or new lines or, click here for examples